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PGC-1/spargel counteracts high fat diet-induced obesity and cardiac lipotoxicity downstream of TOR and Brummer ATGL lipase
Obesity and metabolic syndrome are associated with an increased risk for lipotoxic cardiomyopathy, which is strongly correlated with excessive accumulation of lipids in the heart. Obesity- and type 2 diabetes-related disorders have been linked to altered expression of the transcriptional cofactor PG...
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| Опубликовано в: : | Cell Rep |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560688/ https://ncbi.nlm.nih.gov/pubmed/25753422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.022 |
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