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Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species

Unraveling the gene regulatory networks that govern development and function of the mammalian heart is critical for the rational design of therapeutic interventions in human heart disease. Using the Drosophila heart as a platform for identifying novel gene interactions leading to heart disease, we f...

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書誌詳細
主要な著者: Qian, Li, Wythe, Joshua D., Liu, Jiandong, Cartry, Jerome, Vogler, Georg, Mohapatra, Bhagyalaxmi, Otway, Robyn T., Huang, Yu, King, Isabelle N., Maillet, Marjorie, Zheng, Yi, Crawley, Timothy, Taghli-Lamallem, Ouarda, Semsarian, Christopher, Dunwoodie, Sally, Winlaw, David, Harvey, Richard P., Fatkin, Diane, Towbin, Jeffrey A., Molkentin, Jeffery D., Srivastava, Deepak, Ocorr, Karen, Bruneau, Benoit G., Bodmer, Rolf
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216339/
https://ncbi.nlm.nih.gov/pubmed/21690310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006114
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