Immunoglobulin E and Eosinophil-Dependent Protective Immunity to Larval Onchocerca volvulus in Mice Immunized with Irradiated Larvae

Mice immunized with irradiated Onchocerca volvulus third-stage larvae developed protective immunity. Eosinophil levels were elevated in the parasite microenvironment at the time of larval killing, and measurements of total serum antibody levels revealed an increase in the immunoglobulin E (IgE) leve...

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Publié dans:	Infect Immun
Auteurs principaux:	Abraham, David, Leon, Ofra, Schnyder-Candrian, Silvia, Wang, Chun Chi, Galioto, Ann Marie, Kerepesi, Laura A., Lee, James J., Lustigman, Sara
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2004
Sujets:	Fungal and Parasitic Infections
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321619/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.2.810-817.2004
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