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Immunoglobulin E and Eosinophil-Dependent Protective Immunity to Larval Onchocerca volvulus in Mice Immunized with Irradiated Larvae

Mice immunized with irradiated Onchocerca volvulus third-stage larvae developed protective immunity. Eosinophil levels were elevated in the parasite microenvironment at the time of larval killing, and measurements of total serum antibody levels revealed an increase in the immunoglobulin E (IgE) leve...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Abraham, David, Leon, Ofra, Schnyder-Candrian, Silvia, Wang, Chun Chi, Galioto, Ann Marie, Kerepesi, Laura A., Lee, James J., Lustigman, Sara
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.2.810-817.2004
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