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Immunoglobulin E and Eosinophil-Dependent Protective Immunity to Larval Onchocerca volvulus in Mice Immunized with Irradiated Larvae

Mice immunized with irradiated Onchocerca volvulus third-stage larvae developed protective immunity. Eosinophil levels were elevated in the parasite microenvironment at the time of larval killing, and measurements of total serum antibody levels revealed an increase in the immunoglobulin E (IgE) leve...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Abraham, David, Leon, Ofra, Schnyder-Candrian, Silvia, Wang, Chun Chi, Galioto, Ann Marie, Kerepesi, Laura A., Lee, James J., Lustigman, Sara
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.2.810-817.2004
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