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Immunoglobulin E and Eosinophil-Dependent Protective Immunity to Larval Onchocerca volvulus in Mice Immunized with Irradiated Larvae

Mice immunized with irradiated Onchocerca volvulus third-stage larvae developed protective immunity. Eosinophil levels were elevated in the parasite microenvironment at the time of larval killing, and measurements of total serum antibody levels revealed an increase in the immunoglobulin E (IgE) leve...

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Detalhes bibliográficos
Main Authors: Abraham, David, Leon, Ofra, Schnyder-Candrian, Silvia, Wang, Chun Chi, Galioto, Ann Marie, Kerepesi, Laura A., Lee, James J., Lustigman, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321619/
https://ncbi.nlm.nih.gov/pubmed/14742524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.810-817.2004
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