Unit Mass Baseline Resolution for an Intact 148 kDa Therapeutic Monoclonal Antibody by FT-ICR Mass Spectrometry

Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) provides the highest mass resolving power and mass measurement accuracy for unambiguous identification of biomolecules. Previously, the highest-mass protein for which FT-ICR unit mass resolution had been obtained was 115 kDa at...

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Main Authors: Valeja, Santosh G., Kaiser, Nathan K., Xian, Feng, Hendrickson, Christopher L., Rouse, Jason C., Marshall, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215840/
https://ncbi.nlm.nih.gov/pubmed/22011246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202429c
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