Nano-LC FT-ICR Tandem Mass Spectrometry for Top-Down Proteomics: Routine Baseline Unit Mass Resolution of Whole Cell Lysate Proteins up to 72 kDa

Current high-throughput top-down proteomic platforms provide routine identification of proteins less than 25 kDa with 4-D separations. This short communication reports the application of technological developments over the last few years that improve protein identification and characterization for m...

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Detalhes bibliográficos
Main Authors: Tipton, Jeremiah D., Tran, John C., Catherman, Adam D., Ahlf, Dorothy R., Durbin, Kenneth R., Lee, Ji Eun, Kellie, John F., Kelleher, Neil L., Hendrickson, Christopher L., Marshall, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297430/
https://ncbi.nlm.nih.gov/pubmed/22356091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202651v
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