A Robust Two-Dimensional Separation for Top-Down Tandem Mass Spectrometry of the Low-Mass Proteome

For fractionation of intact proteins by molecular weight (MW), a sharply improved two-dimensional (2D) separation is presented to drive reproducible and robust fractionation before top-down mass spectrometry of complex mixtures. The “GELFrEE” (i.e., gel-eluted liquid fraction entrapment electrophore...

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主要な著者: Lee, Ji Eun, Kellie, John F., Tran, John C., Tipton, Jeremiah D., Catherman, Adam D., Thomas, Haylee M., Ahlf, Dorothy R., Durbin, Kenneth R., Vellaichamy, Adaikkalam, Ntai, Ioanna, Marshall, Alan G., Kelleher, Neil L.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830800/
https://ncbi.nlm.nih.gov/pubmed/19747844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2009.08.001
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