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A Robust Two-Dimensional Separation for Top-Down Tandem Mass Spectrometry of the Low-Mass Proteome

For fractionation of intact proteins by molecular weight (MW), a sharply improved two-dimensional (2D) separation is presented to drive reproducible and robust fractionation before top-down mass spectrometry of complex mixtures. The “GELFrEE” (i.e., gel-eluted liquid fraction entrapment electrophore...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Ji Eun, Kellie, John F., Tran, John C., Tipton, Jeremiah D., Catherman, Adam D., Thomas, Haylee M., Ahlf, Dorothy R., Durbin, Kenneth R., Vellaichamy, Adaikkalam, Ntai, Ioanna, Marshall, Alan G., Kelleher, Neil L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830800/
https://ncbi.nlm.nih.gov/pubmed/19747844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2009.08.001
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