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New Reagents for Enhanced Liquid Chromatographic Separation and Charging of Intact Protein Ions for Electrospray Ionization Mass Spectrometry

Electrospray ionization produces multiply charged ions, thereby lowering the mass-to-charge ratio for peptides and small proteins to a range readily accessed by quadrupole ion trap, orbitrap, and ion cyclotron resonance (ICR) mass analyzers (m/z = 400–2,000). For Fourier transform mass analyzers (or...

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Autors principals: Valeja, Santosh G., Tipton, Jeremiah D., Emmett, Mark R., Marshall, Alan G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932825/
https://ncbi.nlm.nih.gov/pubmed/20704305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1016858
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