Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells

Myeloid cells are a feature of most tissues. Here we show that during development, retinal myeloid cells (RMCs) produce Wnt ligands to regulate blood vessel branching. In the mouse retina, where angiogenesis occurs postnatally(1), somatic deletion in RMCs of the Wnt ligand transporter Wntless(2,3) r...

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Hauptverfasser: Stefater, James A., Lewkowich, Ian, Rao, Sujata, Mariggi, Giovanni, Carpenter, April C., Burr, Adam R., Fan, Jieqing, Ajima, Rieko, Molkentin, Jeffery D., Williams, Bart O., Wills-Karp, Marsha, Pollard, Jeffrey, Yamaguchi, Terry, Ferrara, Napoleone, Gerhardt, Holger, Lang, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214992/
https://ncbi.nlm.nih.gov/pubmed/21623369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10085
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