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Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling
Angiogenesis defines the process in which new vessels grow from existing vessels. Using the mouse retina as a model system, we show that cysteine-rich motor neuron 1 (Crim1), a type I transmembrane protein, is highly expressed in angiogenic endothelial cells. Conditional deletion of the Crim1 gene i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879820/ https://ncbi.nlm.nih.gov/pubmed/24353059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.097949 |
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