Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism

Wnt4 and β-catenin are both required for nephrogenesis, but studies using TCF-reporter mice suggest that canonical Wnt signaling is not activated in metanephric mesenchyme (MM) during its conversion to the epithelia of the nephron. To better define the role of Wnt signaling, we treated rat metanephr...

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Main Authors: Tanigawa, Shunsuke, Wang, Honghe, Yang, Yili, Sharma, Nirmala, Tarasova, Nadya, Ajima, Rieko, Yamaguchi, Terry P., Rodriguez, Luis G., Perantoni, Alan O.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049843/
https://ncbi.nlm.nih.gov/pubmed/21256838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.01.012
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