Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism

Wnt4 and β-catenin are both required for nephrogenesis, but studies using TCF-reporter mice suggest that canonical Wnt signaling is not activated in metanephric mesenchyme (MM) during its conversion to the epithelia of the nephron. To better define the role of Wnt signaling, we treated rat metanephr...

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Hauptverfasser: Tanigawa, Shunsuke, Wang, Honghe, Yang, Yili, Sharma, Nirmala, Tarasova, Nadya, Ajima, Rieko, Yamaguchi, Terry P., Rodriguez, Luis G., Perantoni, Alan O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049843/
https://ncbi.nlm.nih.gov/pubmed/21256838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.01.012
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