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Local Guidance of Emerging Vessel Sprouts Requires Soluble Flt-1 (VEGFR-1)

Blood vessel networks form via sprouting of endothelial cells from parent vessels. Extrinsic cues guide sprouts once they leave the initiation site, but these cues are likely insufficient to regulate initial outward movement, and many embryonic vessel networks form in the absence of a strong extrins...

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Detalhes bibliográficos
Main Authors: Chappell, John C, Taylor, Sarah M, Ferrara, Napoleone, Bautch, Victoria L
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747120/
https://ncbi.nlm.nih.gov/pubmed/19758562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.07.011
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