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Flt-1 (VEGFR-1) is Essential for the VEGF-Notch Feedback Loop during Angiogenesis
OBJECTIVE: Vascular endothelial growth factor (VEGF) signaling induces Notch signaling during angiogenesis. Flt-1/VEGF receptor-1 (VEGFR-1) negatively modulates VEGF signaling. Therefore, we tested the hypothesis that disrupted Flt-1 regulation of VEGF signaling causes Notch pathway defects that con...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521230/ https://ncbi.nlm.nih.gov/pubmed/23744993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301805 |
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