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The Epidermal Growth Factor Receptor (EGFR) Is Proteolytically Modified by the Matriptase-Prostasin Serine Protease Cascade in Cultured Epithelial Cells

Prostasin is expressed at the apical surface of normal epithelial cells and suppresses in vitro invasion of cancer cells. Prostasin re-expression in the PC-3 prostate carcinoma cells down-regulated the epidermal growth factor receptor (EGFR) protein expression and EGF-induced phosphorylation of the...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Mengqian, Chen, Li-Mei, Lin, Chen-Yong, Chai, Karl X.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214967/
https://ncbi.nlm.nih.gov/pubmed/18054338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2007.10.019
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