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Zac1 is a histone acetylation-regulated NF-κB suppressor that mediates histone deacetylase inhibitor-induced apoptosis

Histone deacetylase (HDAC) inhibitors are a class of promising anticancer reagents. They are able to induce apoptosis in embryonic carcinoma (EC) cells. However, the underlying mechanism remains poorly understood. Here we show that increased expression of zinc-finger protein regulator of apoptosis a...

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Détails bibliographiques
Auteurs principaux: Shu, G, Tang, Y, Zhou, Y, Wang, C, Song, J-G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214906/
https://ncbi.nlm.nih.gov/pubmed/21546906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.51
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