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Zac1 is a histone acetylation-regulated NF-κB suppressor that mediates histone deacetylase inhibitor-induced apoptosis

Histone deacetylase (HDAC) inhibitors are a class of promising anticancer reagents. They are able to induce apoptosis in embryonic carcinoma (EC) cells. However, the underlying mechanism remains poorly understood. Here we show that increased expression of zinc-finger protein regulator of apoptosis a...

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Bibliografiske detaljer
Main Authors: Shu, G, Tang, Y, Zhou, Y, Wang, C, Song, J-G
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214906/
https://ncbi.nlm.nih.gov/pubmed/21546906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.51
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