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Assessing the Impact of Non-Differential Genotyping Errors on Rare Variant Tests of Association
BACKGROUND/AIMS: We aim to quantify the effect of non-differential genotyping errors on the power of rare variant tests and identify those situations when genotyping errors are most harmful. METHODS: We simulated genotype and phenotype data for a range of sample sizes, minor allele frequencies, dise...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
S. Karger AG
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214826/ https://ncbi.nlm.nih.gov/pubmed/22004945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000332222 |
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