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Evaluating methods for combining rare variant data in pathway-based tests of genetic association

Analyzing sets of genes in genome-wide association studies is a relatively new approach that aims to capitalize on biological knowledge about the interactions of genes in biological pathways. This approach, called pathway analysis or gene set analysis, has not yet been applied to the analysis of rar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petersen, Ashley, Sitarik, Alexandra, Luedtke, Alexander, Powers, Scott, Bekmetjev, Airat, Tintle, Nathan L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287885/
https://ncbi.nlm.nih.gov/pubmed/22373429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S48
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