Embryonic Lethality, Decreased Erythropoiesis, and Defective Octamer-Dependent Promoter Activation in Oct-1-Deficient Mice

Oct-1 is a sequence-specific DNA binding transcription factor that is believed to regulate a large group of tissue-specific and ubiquitous genes. Both Oct-1 and the related but tissue-restricted Oct-2 protein bind to a DNA sequence termed the octamer motif (5′-ATGCAAAT-3′) with equal affinity in vit...

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Detalles Bibliográficos
Main Authors: Wang, Victoria E. H., Schmidt, Tara, Chen, Jianzhu, Sharp, Phillip A., Tantin, Dean
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC321444/
https://ncbi.nlm.nih.gov/pubmed/14729950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.3.1022-1032.2004
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