Embryonic Lethality, Decreased Erythropoiesis, and Defective Octamer-Dependent Promoter Activation in Oct-1-Deficient Mice

Oct-1 is a sequence-specific DNA binding transcription factor that is believed to regulate a large group of tissue-specific and ubiquitous genes. Both Oct-1 and the related but tissue-restricted Oct-2 protein bind to a DNA sequence termed the octamer motif (5′-ATGCAAAT-3′) with equal affinity in vit...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wang, Victoria E. H., Schmidt, Tara, Chen, Jianzhu, Sharp, Phillip A., Tantin, Dean
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC321444/
https://ncbi.nlm.nih.gov/pubmed/14729950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.3.1022-1032.2004
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires