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Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers

OBJECTIVE: CpG island (CGI) hypermethylation at discrete loci is a prevalent cancer-promoting abnormality in sporadic colorectal carcinomas (S-CRCs). We investigated genome-wide CGI methylation in inflammatory bowel disease (IBD)-associated CRCs (IBD-CRCs). DESIGN: Methylation microarray analyses we...

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Detalhes bibliográficos
Main Authors: Olaru, Alexandru V., Cheng, Yulan, Agarwal, Rachana, Yang, Jian, David, Stefan, Abraham, John M., Yu, Wayne, Lazarev, Mark, Brant, Steven R., Marohn, Michael R., Hutcheon, David F., Harpaz, Noam, Meltzer, Stephen J., Mori, Yuriko
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214229/
https://ncbi.nlm.nih.gov/pubmed/21830278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21826
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