Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers

OBJECTIVE: CpG island (CGI) hypermethylation at discrete loci is a prevalent cancer-promoting abnormality in sporadic colorectal carcinomas (S-CRCs). We investigated genome-wide CGI methylation in inflammatory bowel disease (IBD)-associated CRCs (IBD-CRCs). DESIGN: Methylation microarray analyses we...

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Autores principales: Olaru, Alexandru V., Cheng, Yulan, Agarwal, Rachana, Yang, Jian, David, Stefan, Abraham, John M., Yu, Wayne, Lazarev, Mark, Brant, Steven R., Marohn, Michael R., Hutcheon, David F., Harpaz, Noam, Meltzer, Stephen J., Mori, Yuriko
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214229/
https://ncbi.nlm.nih.gov/pubmed/21830278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21826
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