Anti-Transforming Growth Factor ß Antibody Treatment Rescues Bone Loss and Prevents Breast Cancer Metastasis to Bone

Breast cancer often metastasizes to bone causing osteolytic bone resorption which releases active TGFβ. Because TGFβ favors progression of breast cancer metastasis to bone, we hypothesized that treatment using anti-TGFβ antibody may reduce tumor burden and rescue tumor-associated bone loss in metast...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Biswas, Swati, Nyman, Jeffry S., Alvarez, JoAnn, Chakrabarti, Anwesa, Ayres, Austin, Sterling, Julie, Edwards, James, Rana, Tapasi, Johnson, Rachelle, Perrien, Daniel S., Lonning, Scott, Shyr, Yu, Matrisian, Lynn M., Mundy, Gregory R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214031/
https://ncbi.nlm.nih.gov/pubmed/22096521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027090
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