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Doxorubicin-Mediated Bone Loss in Breast Cancer Bone Metastases Is Driven by an Interplay between Oxidative Stress and Induction of TGFβ

Breast cancer patients, who are already at increased risk of developing bone metastases and osteolytic bone damage, are often treated with doxorubicin. Unfortunately, doxorubicin has been reported to induce damage to bone. Moreover, we have previously reported that doxorubicin treatment increases ci...

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Detalhes bibliográficos
Main Authors: Rana, Tapasi, Chakrabarti, Anwesa, Freeman, Michael, Biswas, Swati
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813496/
https://ncbi.nlm.nih.gov/pubmed/24205081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078043
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