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Loss of Nrf2 accelerates ionizing radiation-induced bone loss by upregulating RANKL

Radiation therapy is an integral part of treatment for cancer patients; however, major side effects of this modality include aberrant bone remodeling and bone loss. Ionizing radiation (IR) is a major external factor that contributes to a significant increase in oxidative stress such as reactive oxyg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rana, Tapasi, Schultz, Michelle A., Freeman, Michael L., Biswas, Swati
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762920/
https://ncbi.nlm.nih.gov/pubmed/23085426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.10.536
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