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N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex

Although many eukaryotic proteins are N-terminally acetylated, structural mechanisms by which N-terminal acetylation mediates protein interactions are largely unknown. Here we found that N-terminal acetylation of the E2 enzyme, Ubc12, dictates distinctive E3-dependent ligation of the ubiquitin-like...

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書誌詳細
主要な著者: Scott, Daniel C., Monda, Julie K., Bennett, Eric J., Harper, J. Wade, Schulman, Brenda A.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214010/
https://ncbi.nlm.nih.gov/pubmed/21940857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1209307
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