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N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex
Although many eukaryotic proteins are N-terminally acetylated, structural mechanisms by which N-terminal acetylation mediates protein interactions are largely unknown. Here we found that N-terminal acetylation of the E2 enzyme, Ubc12, dictates distinctive E3-dependent ligation of the ubiquitin-like...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214010/ https://ncbi.nlm.nih.gov/pubmed/21940857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1209307 |
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