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Mechanism of actin N-terminal acetylation

About 80% of human proteins are amino-terminally acetylated (Nt-acetylated) by one of seven Nt-acetyltransferases (NATs). Actin, the most abundant protein in the cytoplasm, has its own dedicated NAT, NAA80, which acts posttranslationally and affects cytoskeleton assembly and cell motility. Here, we...

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Publicat a:Sci Adv
Autors principals: Rebowski, Grzegorz, Boczkowska, Malgorzata, Drazic, Adrian, Ree, Rasmus, Goris, Marianne, Arnesen, Thomas, Dominguez, Roberto
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141826/
https://ncbi.nlm.nih.gov/pubmed/32284999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay8793
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