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Prostaglandin E(2) protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction

Prostaglandin E(2) (PGE(2)) is a lipid mediator that is produced via the metabolism of arachidonic acid by cyclooxygenase enzymes. In the lung, PGE(2) acts as an anti-inflammatory factor and plays an important role in tissue repair processes. Although several studies have examined the role of PGE(2)...

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Hlavní autoři: Dackor, Ryan T., Cheng, Jennifer, Voltz, James W., Card, Jeffrey W., Ferguson, Catherine D., Garrett, Ryan C., Bradbury, J. Alyce, DeGraff, Laura M., Lih, Fred B., Tomer, Kenneth B., Flake, Gordon P., Travlos, Gregory S., Ramsey, Randle W., Edin, Matthew L., Morgan, Daniel L., Zeldin, Darryl C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213994/
https://ncbi.nlm.nih.gov/pubmed/21856819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00176.2011
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