Cyclooxygenase-2 Regulates Th17 Cell Differentiation during Allergic Lung Inflammation

Rationale: Th17 cells comprise a distinct lineage of proinflammatory T helper cells that are major contributors to allergic responses. It is unknown whether cyclooxygenase (COX)-derived eicosanoids regulate Th17 cells during allergic lung inflammation. Objectives: To determine the role of COX metabo...

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Hauptverfasser: Li, Hong, Bradbury, J. Alyce, Dackor, Ryan T., Edin, Matthew L., Graves, Joan P., DeGraff, Laura M., Wang, Ping Ming, Bortner, Carl D., Maruoka, Shuichiro, Lih, Fred B., Cook, Donald N., Tomer, Kenneth B., Jetten, Anton M., Zeldin, Darryl C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2011
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172888/
https://ncbi.nlm.nih.gov/pubmed/21474648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201010-1637OC
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