Contribution of alveolar type II cell–derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis

Cyclooxygenase (COX)-2 has been shown to be involved in regulating basal airway function, bacterial LPS-induced airway hyperresponsiveness (AHR) and lung inflammation, and bleomycin-induced lung fibrosis; however, the cellular source of COX-2 that underlies these effects is unknown. We generated mic...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Cheng, Jennifer, Dackor, Ryan T., Bradbury, J. Alyce, Li, Hong, DeGraff, Laura M., Hong, Lee K., King, Debra, Lih, Fred B., Gruzdev, Artiom, Edin, Matthew L., Travlos, Gregory S., Flake, Gordon P., Tomer, Kenneth B., Zeldin, Darryl C.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2016
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684524/
https://ncbi.nlm.nih.gov/pubmed/26396235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268458
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