Role for PKCβ in enhanced endothelin-1-induced pulmonary vasoconstrictor reactivity following intermittent hypoxia

Intermittent hypoxia (IH) resulting from sleep apnea causes both systemic and pulmonary hypertension. Enhanced endothelin-1 (ET-1)-induced vasoconstrictor reactivity is thought to play a central role in the systemic hypertensive response to IH. However, whether IH similarly increases pulmonary vasor...

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Autori principali: Snow, Jessica B., Gonzalez Bosc, Laura V., Kanagy, Nancy L., Walker, Benjimen R., Resta, Thomas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213992/
https://ncbi.nlm.nih.gov/pubmed/21803871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00020.2011
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