ApoB siRNA-induced Liver Steatosis is Resistant to Clearance by the Loss of Fatty Acid Transport Protein 5 (Fatp5)

The association between hypercholesterolemia and elevated serum apolipoprotein B (APOB) has generated interest in APOB as a therapeutic target for patients at risk of developing cardiovascular disease. In the clinic, mipomersen, an antisense oligonucleotide (ASO) APOB inhibitor, was associated with...

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Autori principali: Ason, Brandon, Castro-Perez, Jose, Tep, Samnang, Stefanni, Alice, Tadin-Strapps, Marija, Roddy, Thomas, Hankemeier, Thomas, Hubbard, Brian, Sachs, Alan B., Michael Flanagan, W., Kuklin, Nelly A., Mitnaul, Lyndon J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213337/
https://ncbi.nlm.nih.gov/pubmed/21826528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-011-3596-3
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