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HYDROGEN-BOND ENERGETICS DRIVE HELIX FORMATION IN MEMBRANE INTERFACES
The free energy cost ΔG of partitioning many unfolded peptides into membrane interfaces is unfavorable due to the cost of partitioning backbone peptide bonds. The partitioning cost is dramatically reduced if the peptide bonds participate in hydrogen bonds. The reduced cost underlies secondary struct...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213303/ https://ncbi.nlm.nih.gov/pubmed/21802405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.07.019 |
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