Rapid Colorimetric Testing for Pyrazinamide Susceptibility of M. tuberculosis by a PCR-Based In-Vitro Synthesized Pyrazinamidase Method

Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug. But PZA susceptibility test is challenging because PZA activity is optimal only in an acid environment that inhibits the growth of M. tuberculosis. For current phenotypic methods, inconsistent results between different labs have b...

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Autors principals: Zhou, Man, Geng, Xuelei, Chen, Jun, Wang, Xude, Wang, Dianbing, Deng, Jiaoyu, Zhang, Zhiping, Wang, Weihua, Zhang, Xian-En, Wei, Hongping
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213173/
https://ncbi.nlm.nih.gov/pubmed/22102918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027654
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