Rapid Colorimetric Testing for Pyrazinamide Susceptibility of M. tuberculosis by a PCR-Based In-Vitro Synthesized Pyrazinamidase Method

Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug. But PZA susceptibility test is challenging because PZA activity is optimal only in an acid environment that inhibits the growth of M. tuberculosis. For current phenotypic methods, inconsistent results between different labs have b...

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Main Authors: Zhou, Man, Geng, Xuelei, Chen, Jun, Wang, Xude, Wang, Dianbing, Deng, Jiaoyu, Zhang, Zhiping, Wang, Weihua, Zhang, Xian-En, Wei, Hongping
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213173/
https://ncbi.nlm.nih.gov/pubmed/22102918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027654
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