Rapid Colorimetric Testing for Pyrazinamide Susceptibility of M. tuberculosis by a PCR-Based In-Vitro Synthesized Pyrazinamidase Method

Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug. But PZA susceptibility test is challenging because PZA activity is optimal only in an acid environment that inhibits the growth of M. tuberculosis. For current phenotypic methods, inconsistent results between different labs have b...

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Detalhes bibliográficos
Main Authors: Zhou, Man, Geng, Xuelei, Chen, Jun, Wang, Xude, Wang, Dianbing, Deng, Jiaoyu, Zhang, Zhiping, Wang, Weihua, Zhang, Xian-En, Wei, Hongping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213173/
https://ncbi.nlm.nih.gov/pubmed/22102918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027654
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