The Role of the P2X(7) Receptor in Infectious Diseases

ATP is an extracellular signal for the immune system, particularly during an inflammatory response. It is sensed by the P2X(7) receptor, the expression of which is upregulated by pro-inflammatory cytokines. Activation of the P2X(7) receptor opens a cation-specific channel that alters the ionic envir...

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Hlavní autoři: Miller, Catherine M., Boulter, Nicola R., Fuller, Stephen J., Zakrzewski, Alana M., Lees, Michael P., Saunders, Bernadette M., Wiley, James S., Smith, Nicholas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213081/
https://ncbi.nlm.nih.gov/pubmed/22102807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002212
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