P2X(7) receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages

The P2X(7) receptor (P2X(7)R) is highly expressed on the macrophage cell surface and activation of infected cells by extracellular ATP has been shown to kill intracellular bacteria and parasites. Furthermore, single nucleotide polymorphisms (SNPs) that decrease receptor function reduce the ability o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lees, Michael P., Fuller, Stephen J., McLeod, Rima, Boulter, Nicola R., Miller, Catherine M., Zakrzewski, Alana M., Mui, Ernest J., Witola, William H., Coyne, Jessica J., Hargrave, Aubrey C., Jamieson, Sarra E., Blackwell, Jenefer M., Wiley, James S., Smith, Nicholas C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931343/
https://ncbi.nlm.nih.gov/pubmed/20488797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000012
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