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An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify g...

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Detalhes bibliográficos
Publicado no:Mem Inst Oswaldo Cruz
Main Authors: Syn, Genevieve, Blackwell, Jenefer M, Jamieson, Sarra E, Francis, Richard W
Formato: Artigo
Idioma:Inglês
Publicado em: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963570/
https://ncbi.nlm.nih.gov/pubmed/29846382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760170471
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