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An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify g...

詳細記述

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書誌詳細
出版年:Mem Inst Oswaldo Cruz
主要な著者: Syn, Genevieve, Blackwell, Jenefer M, Jamieson, Sarra E, Francis, Richard W
フォーマット: Artigo
言語:Inglês
出版事項: Instituto Oswaldo Cruz, Ministério da Saúde 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963570/
https://ncbi.nlm.nih.gov/pubmed/29846382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760170471
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