An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify g...

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Bibliografische gegevens
Gepubliceerd in:Mem Inst Oswaldo Cruz
Hoofdauteurs: Syn, Genevieve, Blackwell, Jenefer M, Jamieson, Sarra E, Francis, Richard W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Onderwerpen:
Short Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963570/
https://ncbi.nlm.nih.gov/pubmed/29846382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760170471
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