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An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation
Toxoplasma gondii uses epigenetic mechanisms to regulate both endogenous and host cell gene expression. To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins. Step 1 employs PredictNLS and NucPred to identify g...
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| 發表在: | Mem Inst Oswaldo Cruz |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Instituto Oswaldo Cruz, Ministério da Saúde
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963570/ https://ncbi.nlm.nih.gov/pubmed/29846382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760170471 |
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