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Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations

BACKGROUND: Several mutations were present in the genome of Streptococcus pneumoniae linezolid-resistant strains but the role of several of these mutations had not been experimentally tested. To analyze the role of these mutations, we reconstituted resistance by serial whole genome transformation of...

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Autors principals: Billal, Dewan S, Feng, Jie, Leprohon, Philippe, Légaré, Danielle, Ouellette, Marc
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212830/
https://ncbi.nlm.nih.gov/pubmed/22004526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-512
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