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Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations

BACKGROUND: Several mutations were present in the genome of Streptococcus pneumoniae linezolid-resistant strains but the role of several of these mutations had not been experimentally tested. To analyze the role of these mutations, we reconstituted resistance by serial whole genome transformation of...

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Detalhes bibliográficos
Main Authors: Billal, Dewan S, Feng, Jie, Leprohon, Philippe, Légaré, Danielle, Ouellette, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212830/
https://ncbi.nlm.nih.gov/pubmed/22004526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-512
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