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Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations

BACKGROUND: Several mutations were present in the genome of Streptococcus pneumoniae linezolid-resistant strains but the role of several of these mutations had not been experimentally tested. To analyze the role of these mutations, we reconstituted resistance by serial whole genome transformation of...

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Autori principali: Billal, Dewan S, Feng, Jie, Leprohon, Philippe, Légaré, Danielle, Ouellette, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212830/
https://ncbi.nlm.nih.gov/pubmed/22004526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-512
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