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Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana

Dihydrodipicolinate synthase (DHDPS; EC 4.2.1.52) catalyzes the first committed step of the lysine-biosynthetic pathway in plants and bacteria. Since (S)-lysine biosynthesis does not occur in animals, DHDPS is an attractive target for rational antibiotic and herbicide design. Here, the cloning, expr...

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Detalhes bibliográficos
Main Authors: Griffin, Michael D. W., Billakanti, Jagan M., Gerrard, Juliet A., Dobson, Renwick C. J., Pearce, F. Grant
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212457/
https://ncbi.nlm.nih.gov/pubmed/22102238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111033276
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