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Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis

Many biologically active macrocycles contain a C–C double bond through which various other derivatives are prepared; the stereochemical identity of the alkene or the resulting moieties can be critical to the beneficial properties of such molecules. Catalytic ring-closing metathesis (RCM) is a widely...

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Détails bibliographiques
Auteurs principaux: Yu, Miao, Wang, Chenbo, Kyle, Andrew F., Jakubec, Pavol, Dixon, Darren J., Schrock, Richard R., Hoveyda, Amir H.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211109/
https://ncbi.nlm.nih.gov/pubmed/22051677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10563
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