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Proteasome malfunction activates macroautophagy in the heart

Protein quality control (PQC) senses and repairs misfolded/unfolded proteins and, if the repair fails, degrades the terminally misfolded polypeptides through an intricate collaboration between molecular chaperones and targeted proteolysis. Proteolysis of damaged proteins is performed primarily by th...

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Podrobná bibliografie
Hlavní autoři: Zheng, Qingwen, Su, Huabo, Tian, Zongwen, Wang, Xuejun
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211094/
https://ncbi.nlm.nih.gov/pubmed/22081794
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