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p62 Stages an Interplay between the Ubiquitin-Proteasome System and Autophagy in the Heart of Defense against Proteotoxic Stress

As exemplified by desmin-related cardiomyopathy and myocardial ischemia/reperfusion injury, proteasome functional insufficiency plays an essential pathogenic role in the progression of cardiac diseases with elevated proteotoxic stress. Upregulation of p62/SQSTM1 and increased selective autophagy in...

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Bibliografiske detaljer
Main Authors: Su, Huabo, Wang, Xuejun
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424486/
https://ncbi.nlm.nih.gov/pubmed/22902070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2012.05.015
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