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p62 Stages an Interplay between the Ubiquitin-Proteasome System and Autophagy in the Heart of Defense against Proteotoxic Stress
As exemplified by desmin-related cardiomyopathy and myocardial ischemia/reperfusion injury, proteasome functional insufficiency plays an essential pathogenic role in the progression of cardiac diseases with elevated proteotoxic stress. Upregulation of p62/SQSTM1 and increased selective autophagy in...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424486/ https://ncbi.nlm.nih.gov/pubmed/22902070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2012.05.015 |
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