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The interplay between autophagy and the ubiquitin-proteasome system in cardiac proteotoxicity
Proteotoxicity refers to the detrimental effects of damaged/misfolded proteins on the cell. Cardiac muscle is particularly susceptible to proteotoxicity because sustained and severe proteotoxic stress leads to cell death and cardiac muscle has very limited self-renewal capacity. The ubiquitin-protea...
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| Veröffentlicht in: | Biochim Biophys Acta |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277934/ https://ncbi.nlm.nih.gov/pubmed/25092168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.07.028 |
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