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The interplay between autophagy and the ubiquitin-proteasome system in cardiac proteotoxicity

Proteotoxicity refers to the detrimental effects of damaged/misfolded proteins on the cell. Cardiac muscle is particularly susceptible to proteotoxicity because sustained and severe proteotoxic stress leads to cell death and cardiac muscle has very limited self-renewal capacity. The ubiquitin-protea...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Wang, Changhua, Wang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277934/
https://ncbi.nlm.nih.gov/pubmed/25092168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.07.028
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